RELiZORB® (iMMOBILIZED LIPASE) CARTRIDGE Skip to content

RELiZORB Hydrolyzes Fats Prior to Ingestion

RELiZORB is a digestive enzyme cartridge that contains iLipase® and connects in-line with enteral feeding systems. Lipase is covalently bound to small white beads inside the RELiZORB cartridge and is retained in the cartridge during use by two filters. Enteral formula flows through, allowing for fat breakdown and the immediate delivery of absorbable fatty acids and monoglycerides to the gastrointestinal (GI) tract.

iLipase is made up of the digestive enzyme lipase attached to small polymeric microbead carriers and is stored within the RELiZORB cartridge

RELiZORB is proven to hydrolyze available fats,* including medium-chain triglycerides (MCTs) and long-chain triglycerides (LCTs).1

  • The iLipase in RELiZORB is intended to selectively break down triglycerides at the sn-1 and sn-3 positions.
  • LCTs are complex and contain essential fatty acids. Compared to MCTs, LCTs are harder to hydrolyze2 and provide ~10% more calories.1
>90% fat hydrolysis* with RELiZORB - Freedman

cartridge

cartridge

*Greater than 90% of available fats hydrolyzed in most enteral formulas tested, including Nutren 2.0, Impact Peptide 1.5, Peptamen 1.5, Peptamen AF, and Nutren 1.0. Percentage of fat hydrolysis is estimated based on label claim for content, calculated using 500 mL of formula with a pump rate of 120 mL/hr. Please see full list of compatible formulas.

RELiZORB resources are available to support healthcare professionals

Below you can find links to resources (for both inpatient and outpatient services) designed to help your practice or hospital.

References
  1. Freedman S. Options for Addressing Exocrine Pancreatic Insufficiency in Patients Receiving Enteral Nutrition Supplementation. Am J Manag Care. 2017 Jul;23(12 Suppl):S220-S228.
  2. Shah ND, Limketkai BN. The Use of Medium-Chain Triglycerides in Gastrointestinal Disorders. Practical Gastroenterology. 2017 Feb;41(2):20-28.