Consequences of Fat Malabsorption

GI symptoms associated with fat malabsorption¹:

Steatorrhea
Nausea
Constipation
Abdominal pain
Bloating
Diarrhea

Among patients with cystic fibrosis, fat malabsorption is associated with a low BMI and poor outcomes, which can have an impact on²:

Digestive
symptoms
Physical
functioning
Body image
Treatment burden
Nutritional status
Pain

In critically ill patient in the ICU, an inflammation-modulating diet enriched with EPA and-linolenic acid GLA resulted in³:

83% risk reduction of developing new organ failures

60% risk reduction of 28-day in-hospital all-cause mortality

~5 fewer days on mechanical ventilation

~4 fewer days in the ICU

Overall short- and long-term health impacts are multisystemic and varied^4-6

Weight loss
Respiratory
issues
Intestinal
obstructions
Infections
Diabetes
Impaired bone health
(vitamin K deficiency)
Death

GI=gastrointestinal.
BMI=body mass index.
ICU=intensive care unit.

REFERENCES
1. Blaauw R. Malabsorption: causes, consequences, diagnosis and treatment. S Afr J Clin Nutr. 2011;24(3):125-127.
2. Bodnar R, Kadar L, Holics K, et al. Factors influencing quality of life and disease severity in Hungarian children and young adults with cystic fibrosis. Ital J Pediatr. 2014;2:40-50.
3. Martin JM, Stapleton RD. Omega-3 fatty acids in critical illness. Nutr Rev. 2010;68(9):531-541.
4. Mayo Clinic Website. Cystic fibrosis: symptoms and causes. http://www.mayoclinic.org/diseases-conditions/cystic-fibrosis/symptoms-causes/dxc-20211893. Accessed October 16, 2017.
5. Kalnins D, Wilschanski M. Maintenance of nutritional status in patients with cystic fibrosis: new and emerging therapies. Drug Des Devel Ther. 2012;6:151-161.
6. Dominguez-Munoz JE. Pancreatic exocrine insufficiency: diagnosis and treatment. J Gastroenterol Hepatol. 2011;26(Suppl 2):12-16.

Fat Malabsorption Has Devastating Consequences

GI symptoms associated with fat malabsorption1:

Among patients with cystic fibrosis, fat malabsorption is associated with a low BMI and poor outcomes, which can have an impact on2:

In critically ill patient in the ICU, an inflammation-modulating diet enriched with EPA and-linolenic acid GLA resulted in3:

Overall short- and long-term health impacts are multisystemic and varied4-6

Final Sequance (vimeo 720p)

GI symptoms associated with fat malabsorption¹:

Among patients with cystic fibrosis, fat malabsorption is associated with a low BMI and poor outcomes, which can have an impact on²:

In critically ill patient in the ICU, an inflammation-modulating diet enriched with EPA and-linolenic acid GLA resulted in³:

Overall short- and long-term health impacts are multisystemic and varied^4-6